Title |
Cancer and Leukemia Group B
|
Institution |
DANA-FARBER CANCER INSTITUTE, BOSTON, MA
|
Principal Investigator |
Burstein, Harold
|
NCI Program Director |
Margaret Mooney
|
Cancer Activity |
Clinical Trials
|
Division |
DCTD
|
Funded Amount |
$413,820
|
Project Dates |
04/01/1982 - 03/31/2015
|
Fiscal Year |
2009
|
Project Type |
Grant
|
Research Topics w/ Percent Relevance |
Cancer Types w/ Percent Relevance |
Cancer (100.0%)
Childhood Cancers (6.0%)
Aging (2.0%)
Cancer Survivorship (21.0%)
Chemotherapy (99.0%)
Digestive Diseases (23.0%)
Surgery (3.0%)
Taxol (45.0%)
|
Breast (41.0%)
Childhood Leukemia (6.0%)
Colon/Rectum (16.0%)
Esophagus (7.0%)
Leukemia (6.0%)
Lung (4.0%)
Multiple Myeloma (17.0%)
Non Hodgkins Lymphoma (4.0%)
Prostate (6.0%)
|
Research Type |
Localized Therapies - Clinical Applications
Systemic Therapies - Clinical Applications
|
Abstract |
DESCRIPTION (provided by applicant): The Dana-Farber Cancer Institute (DFCI) and Dana-Farber/Partners CancerCare (DF/PCC) proposes to use its membership in the Cancer and Leukemia Group B (CALGB) to support participation in therapeutic research and other clinical trials, both in the Institute and its affiliate institutions. The goals of this project will be the initiation and participation in Phase I, II and III cooperative clinical trials involving chemotherapy, surgery and radiation therapy. A major emphasis will be made in developing new therapeutic strategies both at DFCI, MGH and in pilot collaborative investigations with interested members of CALGB. Dana-Farber investigators would continue to be actively involved in disease and modality committees of the CALGB. This project is designed to bring cooperative group trials to regional community hospitals affilaited through the Dana-Farber Cancer Institute throughout New England.
PRINCIPAL INVESTIGATOR:
The PI of this grant has changed in the reporting period, from Dr. George Canellos to Dr. Eric Winer. Dr. Winer also serves as head of the DFCI Breast Cancer Program and co-chair of the CALGB Breast Cancer Committee. He is extremely well qualified for this position, with an excellent track record of leadership.
PROTECTION OF HUMAN SUBJECTS (Resume): ACCEPTABLE
Safeguards are adequate.
INCLUSION OF WOMEN PLAN (Resume): ACCEPTABLE
Accrual of women is acceptable.
INCLUSION OF MINORITIES PLAN (Resume): ACCEPTABLE
Minority accrual is acceptable.
INCLUSION OF CHILDREN PLAN (Resume): ACCEPTABLE
Subjects older than age 18 are enrolled.
OVERALL RECOMMENDATION:
This application is rated excellent and is recommended for six years of support. |